Sodium Spurs a Tadpole to Regenerate Its Tail
from : http://www.basesciences.com/article.asp?articleid=98927&Sodium-Spurs-a-Tadpole-to-Regenerate-Its-Tail if a young tadpole loses its tail, no problem—it can grow a new one. Biologist Michael Levin and his team experimented with this amphibian talent, and they say they found the signal that triggers the regeneration: sodium. If scientists can find the trigger in tadpoles, perhaps someday they could find triggers for other species. Maybe even humans. By using drugs to prompt a flood of sodium ions into injured nerve cells, biologists from Tufts University were able to regenerate severed tadpole tails — complex appendages containing spinal cord, muscle and other tissue. The sodium infusion got tadpoles to regrow lost tails even if scar tissue had already formed over the wound. Conversely, blocking the flow of sodium ions to the nerve cells prevented the regeneration. One particular [sodium]-importing channel, called NaV1.2, was required for tail re...